TAB2 antibody

• Background:

  Adapter linking MAP3K7/TAK1 and TRAF6. Promotes MAP3K7 activation in the IL1 signaling pathway. The binding of 'Lys-63'-linked polyubiquitin chains to TAB2 promotes autophosphorylation of MAP3K7 at 'Thr-187'. Involved in heart development.

• Synonyms:

  TGF-beta-activated kinase 1 and MAP3K7-binding protein 2|Mitogen-activated protein kinase kinase kinase 7-interacting protein 2|TAK1-binding protein 2 (TAB-2) |TGF-beta-activated kinase 1-binding protein 2|TAB2|KIAA0733|MAP3K7IP2

• Gene ID:

  23118

• UniProt:

  Q9NYJ8

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Mitogen-activated protein kinase kinase kinase 7 interacting protein 2

• Target:

  TAB2

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC, IF

• Field of Research:

  Immunology

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  77 kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC, IF

• Immunogen Sequence:

  17-269aa