EGFR antibody

• Background :

  The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

• Synonyms :

  Epidermal growth factor receptor|Proto-oncogene c-ErbB-1|Receptor tyrosine-protein kinase erbB-1|EGFR|ERBB|ERBB1|HER1

• Gene ID :

  1956

• UniProt :

  P00533

• Host :

  Mouse

• Reactivity :

  Human

• Immunogen :

  Epidermal growth factor receptor

• Target :

  EGFR

• Clonality :

  Monoclonal

• Isotype :

  IgG1

• Applications :

  ELISA, WB, IHC

• Field of Research :

  Signal Transduction, Immunology, Cancer

• Purification :

  Protein A+G purified

• Dilution :

  WB: 1:2000 - 1:10000; IHC: 1:100 - 1:1000

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  140-160 kDa

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Clone ID :

  2C9

• Tested Applications :

  ELISA, WB, IHC

• Immunogen Sequence :

  291-534aa