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ST6GAL1 antibody

CAT: 0710-FNab10130Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab10130Size:100 µg
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Background
ST6GAL1 (β-galactoside α-2-6 sialyl transferase1; also known as ST6N or CD75) is a sialyltransferase mediating the glycosylation of proteins and lipids to form functionally important glycoproteins and glycolipids in the Golgi compartment. It is principally expressed in liver, placenta and skeletal muscle. ST6GAL1 undergoes proteolytic process to generate soluble form from membrane form. Western blot analysis of human liver using this antibody detects both isoforms between 43-50 kDa. Higher molecular weight of bands around 50-70 kDa can also be observed with unknown reason.
Synonyms
Beta-galactoside alpha-2,6-sialyltransferase 1 (Alpha 2,6-ST 1) |B-cell antigen CD75|CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1|ST6Gal I (ST6GalI) |Sialyltransferase 1|ST6GAL1|SIAT1
Gene ID
6480
UniProt
P15907
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
ST6 beta-galactosamide alpha-2, 6-sialyltranferase 1
Target
ST6GAL1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IP
Field of Research
Cancer, Immunology, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:300; IP: 1:500 - 1:1000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
50 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IP
Immunogen Sequence
60-406aa

UniProtKB · P15907

Beta-galactoside alpha-2,6-sialyltransferase 1

SIAT1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P15907
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ST6GAL1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
Alpha 2,6-ST 1
EC number
2.4.3.1
Processing
—
Secondary accessions
A8KA14, B2R513, D3DNV3
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

PTM

Disulfide bondGlycoproteinPhosphoprotein

Molecular function

GlycosyltransferaseTransferase

Cellular component

Golgi apparatusMembraneSecreted

Domain

Signal-anchorTransmembraneTransmembrane helix

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