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MGMT antibody

CAT: 0710-FNab10100Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab10100Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
Synonyms
Methylated-DNA--protein-cysteine methyltransferase|6-O-methylguanine-DNA methyltransferase (MGMT) |O-6-methylguanine-DNA-alkyltransferase|MGMT
Gene ID
4255
UniProt
P16455
Host
Rabbit
Reactivity
Human
Immunogen
O-6-methylguanine-DNA methyltransferase
Target
MGMT
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC
Field of Research
Cancer, Immunology, Metabolism
Purification
Immunogen affinity purified
Dilution
IHC: 1:50 - 1:500
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
22 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC

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