RECK antibody

• Background :

  Negatively regulates matrix metalloproteinase-9 (MMP-9) by suppressing MMP-9 secretion and by direct inhibition of its enzymatic activity. RECK down-regulation by oncogenic signals may facilitate tumor invasion and metastasis. Appears to also regulate MMP-2 and MT1-MMP, which are involved in cancer progression.

• Synonyms :

  Reversion-inducing cysteine-rich protein with Kazal motifs (hRECK) |Suppressor of tumorigenicity 15 protein|RECK|ST15

• Gene ID :

  8434

• UniProt :

  O95980

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  Reversion-inducing-cysteine-rich protein with kazal motifs

• Target :

  RECK

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, IHC

• Field of Research :

  Cancer

• Purification :

  Immunogen affinity purified

• Dilution :

  IHC: 1:20-1:200

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  110 kDa

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, IHC