NCOR2 antibody

• Background:

  Transcriptional corepressor. Mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. Isoform 1 and isoform 5 have different affinities for different nuclear receptors. Involved in the regulation BCL6-dependent of the germinal center (GC) reactions, mainly through the control of the GC B-cells proliferation and survival.

• Synonyms:

  Nuclear receptor corepressor 2 (N-CoR2) |CTG repeat protein 26|SMAP270|Silencing mediator of retinoic acid and thyroid hormone receptor (SMRT) |T3 receptor-associating factor (TRAC) |Thyroid-, retinoic-acid-receptor-associated corepressor|NCOR2|CTG26

• Gene ID:

  9612

• UniProt:

  Q9Y618

• Host:

  Rabbit

• Reactivity:

  Human, mouse, Rat

• Immunogen:

  Nuclear receptor co-repressor 2

• Target:

  NCOR2

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC

• Field of Research:

  Metabolism

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:2000; IHC: 1:50-1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  180 kDa, 275 kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC