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VCAM1 antibody

CAT: 0710-FNab09950Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab09950Size:100 µg
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Background
This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene.
Synonyms
Vascular cell adhesion protein 1 (V-CAM 1, VCAM-1) |INCAM-100|Soluble Vascular Cell Adhesion Molecule-1|VCAM1
UniProt
P19320
Host
Mouse
Reactivity
Human, Mouse
Immunogen
Vascular cell adhesion molecule 1
Target
VCAM1
Clonality
Monoclonal
Isotype
IgG1
Applications
ELISA, WB, IHC
Field of Research
Signal Transduction, Cardiovascular, Immunology, Cancer, Neuroscience, Stem Cells
Purification
Protein A+G purified
Dilution
WB: 1:500 - 1:1000; IHC: 1:50 - 1:500
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
105 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
2F7
Tested Applications
ELISA, WB, IHC

UniProtKB · P19320

Vascular cell adhesion protein 1

VCAM1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P19320
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
VCAM1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
V-CAM 1, VCAM-1
EC number
—
Processing
Precursor
Secondary accessions
A8K6R7, B4DKS4, E9PDD1, Q6NUP8
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Cell adhesion

Cellular component

Cell membraneMembraneSecreted

PTM

Disulfide bondGlycoproteinUbl conjugation

Domain

Immunoglobulin domainRepeatSignalTransmembraneTransmembrane helix

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