PARP1 antibody
CAT:
710-FNab09939
Size:
100 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
PARP1 antibody
- Background: PARP1 (poly(ADP-ribose) polymerase 1) is a nuclear enzyme catalyzing the poly(ADP-ribosyl)ation of many key proteins in vivo. The normal function of PARP1 is the routine repair of DNA damage. Activated by DNA strand breaks, the PARP1 is cleaved into an 85 to 89-kDa COOH-terminal fragment and a 24-kDa NH2-terminal peptide by caspases during the apoptotic process. The appearance of PARP fragments is commonly considered as an important biomarker of apoptosis.
- Synonyms: Poly [ADP-ribose] polymerase 1 (PARP-1)|ADP-ribosyltransferase diphtheria toxin-like 1 (ARTD1)|DNA ADP-ribosyltransferase PARP1|NAD(+) ADP-ribosyltransferase 1 (ADPRT 1)|Poly[ADP-ribose] synthase 1|Protein poly-ADP-ribosyltransferase PARP1|Poly [ADP-ribose] polymerase 1, processed C-terminus Alternative names: Poly [ADP-ribose] polymerase 1, 89-kDa form|Poly [ADP-ribose] polymerase 1, processed N-terminus (NT-PARP-1) Alternative names: Poly [ADP-ribose] polymerase 1, 24-kDa form|Poly [ADP-ribose] polymerase 1, 28-kDa form|PARP1|ADPRT|PPOL
- CAS Number: 9007-83-4
- Gene ID: 142
- UniProt: P09874
- Host: Mouse
- Reactivity: Human, Mouse, Rat
- Immunogen: poly (ADP-ribose) polymerase 1
- Target: PARP1
- Clonality: Monoclonal
- Isotype: IgG1
- Clone: 4A9
- Applications: ELISA, WB, IHC, IF
- Field of Research: Metabolism
- Purification: protein A+G purified
- Dilution: WB: 1:5000 - 1:30000; IHC: 1:100 - 1:1000; IF: 1:50 - 1:500
- Purity: ≥95% as determined by SDS-PAGE
- Form: Liquid
- Molecular Weight: 115 kDa, 89 kDa
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)