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SQSTM1 antibody

CAT: 0710-FNab09853Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab09853Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
Synonyms
Sequestosome-1|EBI3-associated protein of 60 kDa (EBIAP, p60) |Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa|Ubiquitin-binding protein p62|SQSTM1|ORCA|OSIL
Gene ID
8878
UniProt
Q13501
Host
Mouse
Reactivity
Human
Immunogen
Sequestosome 1
Target
SQSTM1
Clonality
Monoclonal
Isotype
IgG2a
Applications
ELISA, WB, IHC, IF
Field of Research
Neuroscience, Cardiovascular, Metabolism, Signal Transduction
Purification
Protein A+G purified
Dilution
WB: 1:1000 - 1:4000; IHC: 1:50 - 1:500; IF: 1:20 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
62 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
5H3
Tested Applications
ELISA, WB, IHC, IF
Immunogen Sequence
1-440aa

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