NPPB antibody

• Background:

  NPPB, also known as B-type natriuretic peptide (BNP), is a cardiac hormone that is secreted mainly in the ventricles in response to increased wall stress. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. BNP is a marker of systolic and diastolic dysfunction and a strong predictor of mortality in heart failure patients.

• Synonyms:

  Natriuretic peptides B|Brain natriuretic factor prohormone (preproBNP, proBNP) |Gamma-brain natriuretic peptide|Iso-ANP|NT-proBNP Alternative names: NT-pro-BNP|NT-proBNP (1-76) |proBNP (3-108) |Brain natriuretic peptide 32 (BNP (1-32), BNP-32) Alternative names: Brain natriuretic peptide (BNP) |BNP (1-30) |BNP (1-29) |BNP (1-28) |BNP (2-31) |BNP (3-32) Alternative names: des-SerPro-BNP|proBNP (79-108) |BNP (3-30) |BNP (3-29) |Brain natriuretic peptide 29 (BNP (4-32) ) |BNP (4-31) |BNP (4-30) |BNP (4-29) |BNP (4-27) |BNP (5-32) |BNP (5-31) |BNP (5-29) |NPPB

• Gene ID:

  4879

• UniProt:

  P16860

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Natriuretic peptide precursor B

• Target:

  NPPB

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, IHC

• Field of Research:

  Stem Cells, Cardiovascular

• Purification:

  Immunogen affinity purified

• Dilution:

  IHC: 1:20-1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  15 kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, IHC