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VCL antibody

CAT: 0710-FNab09800Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab09800Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Vinculin belongs to the vinculin/alpha-catenin family. It is an actin filament (F-actin) -binding protein which involved in cell-matrix adhesion and cell-cell adhesion. Vinculin regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. It may also play important roles in cell morphology and locomotion. Vinculin is a 117-kDa, 1,066-amino-acid protein which is ubiquitously expressed. Its splice variant, metavinculin (124 kDa), is muscle-specific.
Synonyms
Vinculin|Metavinculin (MV) |VCL
UniProt
P18206
Host
Mouse
Reactivity
Human, Rat, Mouse
Immunogen
Vinculin
Target
VCL
Clonality
Monoclonal
Isotype
IgG1
Applications
ELISA, FC, IF, IHC, WB
Field of Research
Immunology, Cardiovascular
Purification
Protein A+G purification
Dilution
WB: 1:2000-1:20000; IHC: 1:50-1:500; IF: 1:50-1:500
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
124 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
5E7
Tested Applications
ELISA, FC, IF, IHC, WB

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