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EPCAM antibody

CAT: 0710-FNab09783Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab09783Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Epithelial cell adhesion molecule (EpCAM, CD326) is a type I transmembrane glycoprotein that functions as a homophilic, epithelial-specific intercellular cell-adhesion molecule. In addition to cell adhesion, EpCAM is also involved in cellular signaling, cell migration, proliferation, and differentiation. EpCAM is highly expressed on most carcinomas and therefore of potential use as a diagnostic and prognostic marker for a variety of carcinomas, and has become a therapeutic target. (PMID: 20837599; 19249674; 21576002; 22647938)
Synonyms
Epithelial cell adhesion molecule (Ep-CAM) |Adenocarcinoma-associated antigen|Cell surface glycoprotein Trop-1|Epithelial cell surface antigen|Epithelial glycoprotein (EGP) |Epithelial glycoprotein 314 (EGP314, hEGP314) |KS 1/4 antigen|KSA|Major gastrointestinal tumor-associated protein GA733-2|Tumor-associated calcium signal transducer 1|EPCAM|GA733-2|M1S2|M4S1|MIC18|TACSTD1|TROP1
UniProt
P16422
Host
Mouse
Reactivity
Human
Immunogen
Epithelial cell adhesion molecule
Target
EPCAM
Clonality
Monoclonal
Isotype
IgG1
Applications
ELISA, WB, IHC
Field of Research
Stem Cells, Immunology, Signal Transduction, Cancer
Purification
Protein A+G purification
Dilution
WB: 1:1000-1:10000; IHC: 1:50-1:500
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
36 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
3C8
Tested Applications
ELISA, WB, IHC

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