CD45 antibody

• Background:

  CD45, also known as leukocyte common antigen (LCA), B220, and T200, is a 180-240 kD single chain type I membrane glycoprotein. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes and platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation.

• Synonyms:

  Receptor-type tyrosine-protein phosphatase C|Leukocyte common antigen (L-CA) |T200|PTPRC|CD45

• UniProt:

  P08575

• Host:

  Mouse

• Reactivity:

  Human, Pig

• Immunogen:

  Protein tyrosine phosphatase, receptor type, C

• Target:

  CD45

• Clonality:

  Monoclonal

• Isotype:

  IgG2a

• Applications:

  ELISA, WB, IHC, FC

• Field of Research:

  Signal Transduction, Metabolism, Cardiovascular, Immunology, Cancer, Neuroscience, Stem Cells

• Purification:

  Protein A+G purification

• Dilution:

  WB: 1:1000-1:10000; IHC: 1:20-1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  180-220 kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Clone ID:

  4C8

• Tested Applications:

  ELISA, WB, IHC, FC