CD45 antibody

• Background :

  CD45, also known as leukocyte common antigen (LCA), B220, and T200, is a 180-240 kD single chain type I membrane glycoprotein. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes and platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation.

• Synonyms :

  Receptor-type tyrosine-protein phosphatase C|Leukocyte common antigen (L-CA) |T200|PTPRC|CD45

• UniProt :

  P08575

• Host :

  Mouse

• Reactivity :

  Human, Pig

• Immunogen :

  Protein tyrosine phosphatase, receptor type, C

• Target :

  CD45

• Clonality :

  Monoclonal

• Isotype :

  IgG2a

• Applications :

  ELISA, WB, IHC, FC

• Field of Research :

  Signal Transduction, Metabolism, Cardiovascular, Immunology, Cancer, Neuroscience, Stem Cells

• Purification :

  Protein A+G purification

• Dilution :

  WB: 1:1000-1:10000; IHC: 1:20-1:200

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  180-220 kDa

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Clone ID :

  4C8

• Tested Applications :

  ELISA, WB, IHC, FC