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PGR antibody

CAT: 0710-FNab09774Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab09774Size:100 µg
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Background
This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap.
Synonyms
Progesterone receptor (PR) |Nuclear receptor subfamily 3 group C member 3|PGR|NR3C3
Gene ID
5241
UniProt
P06401
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Progesterone receptor
Target
PGR
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Signal Transduction, Metabolism, Cancer, Immunology, Neuroscience
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
94 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
Immunogen Sequence
636-933aa