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ZYX antibody

CAT: 0710-FNab09765Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab09765Size:100 µg
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Background
Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin (ZYX) is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles.
Synonyms
Zyxin|Zyxin-2|ZYX
Gene ID
7791
UniProt
Q15942
Host
Mouse
Reactivity
Human, Mouse
Immunogen
Zyxin
Target
ZYX
Clonality
Monoclonal
Isotype
IgG1
Applications
ELISA, WB, IHC, IF
Field of Research
Cell Division and Proliferation, Signal Transduction
Purification
Protein A+G purification
Dilution
WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
80 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
8D5
Tested Applications
ELISA, WB, IHC, IF

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