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ZP3 antibody

CAT: 0710-FNab09753Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab09753Size:100 µg
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Background
The mammalian zona pellucida, which mediates species-specific sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy, is composed of three to four glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
Synonyms
Zona pellucida sperm-binding protein 3|Sperm receptor|ZP3A/ZP3B|Zona pellucida glycoprotein 3 (Zp-3) |Zona pellucida protein C|Processed zona pellucida sperm-binding protein 3|ZP3|ZP3A|ZP3B|ZPC
Gene ID
7784
UniProt
P21754
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Zona pellucida glycoprotein 3 (sperm receptor)
Target
ZP3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, WB
Field of Research
Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:2000; IP: 1:200-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
41 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC, WB

UniProtKB · P21754

Zona pellucida sperm-binding protein 3

ZP3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P21754
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ZP3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
Q06633, Q29RW0
Protein keywords

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneExtracellular matrixMembraneSecreted

PTM

Cleavage on pair of basic residuesDisulfide bondGlycoproteinPyrrolidone carboxylic acid

Disease

Disease variant

Biological process

Fertilization

Technical term

Proteomics identificationReference proteome

Molecular function

Receptor

Domain

SignalTransmembraneTransmembrane helix