DAPK3 antibody

• Background:

  ZIP kinase, also named as ZIPK and Dlk, belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family and DAP kinase subfamily. ZIP kinase is a Serine/threonine kinase which acts as a positive regulator of apoptosis. ZIP kinasephosphorylates histone H3 on 'Thr-11' at centromeres during mitosis. ZIP kinase regulates myosin light chain phosphatase through phosphorylation of MYPT1 thereby regulating the assembly of the actin cytoskeleton, cell migration, invasiveness of tumor cells, smooth muscle contraction and neurite outgrowth. It catalyze the reaction: ATP + a protein = ADP + a phosphoprotein.

• Synonyms:

  Death-associated protein kinase 3 (DAP kinase 3) |DAP-like kinase (Dlk) |MYPT1 kinase|Zipper-interacting protein kinase (ZIP-kinase) |DAPK3|ZIPK

• UniProt:

  O43293

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Death-associated protein kinase 3

• Target:

  DAPK3

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IF

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:200-1:1000; IF: 1:20-1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  53 kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IF