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YWHAB antibody

CAT: 0710-FNab09575Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab09575Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2. Negative regulator of signaling cascades that mediate activatation of MAP kinases via AKAP13.
Synonyms
14-3-3 protein beta/alpha|Protein 1054|Protein kinase C inhibitor protein 1 (KCIP-1) |14-3-3 protein beta/alpha, N-terminally processed|YWHAB
Gene ID
7529
UniProt
P31946
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
Target
YWHAB
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC
Field of Research
Neuroscience, Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
28 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC

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