YAP1 antibody

• Background:

  This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.

• Synonyms:

  Transcriptional coactivator YAP1 (Yes-associated protein 1) |Protein yorkie homolog|Yes-associated protein YAP65 homolog|YAP1|YAP65

• Gene ID:

  10413

• UniProt:

  P46937

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Yes-associated protein 1, 65kDa

• Target:

  YAP1

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC, IF, IP

• Field of Research:

  Stem Cells, Signal Transduction, Metabolism

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200; IP: 1:20 - 1:50

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  70 kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC, IF, IP

• Immunogen Sequence:

  350-504aa