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VIL1 antibody

CAT: 0710-FNab09406Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab09406Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Villin 1 (VIL1) is a 95-kd F-actin bundling and severing protein and its expression is restricted to epithelial cells with a brush border, like epithelial cells of the intestinal mucosa, gall bladder, renal proximal tubules and ductuli efferentes of the testis. VIL1 has been reported to be an epithelial cell-specific anti-apoptotic protein, and to have an important function in regulating actin dynamics, cell morphology, epithelial-to-mesenchymal transitions, cell migration and cell survival. In addition, VIL1 is a useful diagnostic marker for of various cancer, like cervical and endometrial adenocarcinomas, renal cell carcinoma. VIL1 was recently identified as a novel biomarker predictive for postoperative recurrence and poorer prognosis of high serum AFP associated HCC.
Synonyms
Villin-1|VIL1|VIL
Gene ID
7429
UniProt
P09327
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Villin 1
Target
VIL1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Cancer, Immunology
Purification
Immunogen affinity purified
Dilution
WB: 1:1000-1:10000; IHC: 1:50-1:8000; IF: 1:20-1:200; IP: 1:200-1:1000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
93 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF

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