UNC5C-Specific antibody

CAT: 0710-FNab09263Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab09263Size:100 µg
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Background
UNC5C, also named as UNC5H3, belongs to the unc-5 family. It is a receptor for netrin required for axon guidance. It mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also involved in corticospinal tract axon guidances independently of DCC. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. The antibody is specific to UNC5C.
Synonyms
Netrin receptor UNC5C|Protein unc-5 homolog 3|Protein unc-5 homolog C|UNC5C|UNC5H3
UniProt
O95185
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Unc-5 homolog C (C. elegans)
Target
UNC5C
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Signal Transduction, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:5000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
103 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

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