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UGDH antibody

CAT: 0710-FNab09238Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab09238Size:100 µg
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Background
The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia. Alternative splicing results in multiple transcript variants.
Synonyms
UDP-glucose 6-dehydrogenase (UDP-Glc dehydrogenase, UDP-GlcDH, UDPGDH) |UGDH
Gene ID
7358
UniProt
O60701
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
UDP-glucose dehydrogenase
Target
UGDH
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
60 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF

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