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DDX39B antibody

CAT: 0710-FNab09142Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab09142Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the DEAD box family of RNA-dependent ATPases that mediate ATP hydrolysis during pre-mRNA splicing. The encoded protein is an essential splicing factor required for association of U2 small nuclear ribonucleoprotein with pre-mRNA, and it also plays an important role in mRNA export from the nucleus to the cytoplasm. This gene belongs to a cluster of genes localized in the vicinity of the genes encoding tumor necrosis factor alpha and tumor necrosis factor beta. These genes are all within the human major histocompatibility complex class III region. Mutations in this gene may be associated with rheumatoid arthritis. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on both chromosomes 6 and 11. Read-through transcription also occurs between this gene and the upstream ATP6V1G2 (ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2) gene.
Synonyms
Spliceosome RNA helicase DDX39B|56 kDa U2AF65-associated protein|ATP-dependent RNA helicase p47|DEAD box protein UAP56|HLA-B-associated transcript 1 protein|DDX39B|BAT1|UAP56
Gene ID
7919
UniProt
Q13838
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
HLA-B associated transcript 1
Target
DDX39B
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Epigenetics
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:100 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
49 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

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