U2AF1 antibody

CAT: 0710-FNab09138Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab09138Size:100 µg
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Background
U2 auxiliary factor (U2AF), comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. U2 (RNU2) small nuclear RNA auxiliary factor 1 (U2AF1, synonyms: RN, FP793, U2AF35, U2AFBP, RNU2AF1) is the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. The U2AF1 gene is localized to chromosome 21q22.3, which is the critical region for three diseases, progressive myoclonus epilepsy, autoimmune polyglandular disease type 1, and one form of bipolar affective disorder.
Synonyms
Splicing factor U2AF 35 kDa subunit|U2 auxiliary factor 35 kDa subunit|U2 small nuclear RNA auxiliary factor 1|U2 snRNP auxiliary factor small subunit|U2AF1|U2AF35|U2AFBP
Gene ID
7307
UniProt
Q01081
Host
Mouse
Reactivity
Human
Immunogen
U2 small nuclear RNA auxiliary factor 1
Target
U2AF1
Clonality
Monoclonal
Isotype
IgG1
Applications
ELISA, WB, IHC, IP
Field of Research
Neuroscience, Metabolism, Epigenetics
Purification
Protein A+G purification
Dilution
WB: 1:500-1:5000; IHC: 1:20-1:200; IP: 1:200-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
38 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
1E9
Tested Applications
ELISA, WB, IHC, IP

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