TULP3 antibody

• Background:

  Negative regulator of the Shh signaling transduction pathway: recruited to primary cilia via association with the IFT complex A (IFT-A) and is required for recruitment of G protein-coupled receptor GPR161 to cilia, a promoter of PKA-dependent basal repression machinery in Shh signaling. Binds to phosphorylated inositide (phosphoinositide) lipids. Both IFT-A-and phosphoinositide-binding properties are required to regulate ciliary G protein-coupled receptor trafficking. Not involved in ciliogenesis.

• Synonyms:

  Tubby-related protein 3|Tubby-like protein 3|TULP3|TUBL3

• Gene ID:

  7289

• UniProt:

  O75386

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Tubby like protein 3

• Target:

  TULP3

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC, IP, IF

• Field of Research:

  Neuroscience, Developmental biology

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:1000; IHC: 1:20-1:200; IP: 1:200-1:1000; IF: 1:20-1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  56 kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC, IP, IF