TULP3 antibody

• Background :

  Negative regulator of the Shh signaling transduction pathway: recruited to primary cilia via association with the IFT complex A (IFT-A) and is required for recruitment of G protein-coupled receptor GPR161 to cilia, a promoter of PKA-dependent basal repression machinery in Shh signaling. Binds to phosphorylated inositide (phosphoinositide) lipids. Both IFT-A-and phosphoinositide-binding properties are required to regulate ciliary G protein-coupled receptor trafficking. Not involved in ciliogenesis.

• Synonyms :

  Tubby-related protein 3|Tubby-like protein 3|TULP3|TUBL3

• Gene ID :

  7289

• UniProt :

  O75386

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Tubby like protein 3

• Target :

  TULP3

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, WB, IHC, IP, IF

• Field of Research :

  Neuroscience, Developmental biology

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500-1:1000; IHC: 1:20-1:200; IP: 1:200-1:1000; IF: 1:20-1:200

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  56 kDa

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, WB, IHC, IP, IF