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TSG101 antibody

CAT: 0710-FNab09040Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab09040Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.
Synonyms
Tumor susceptibility gene 101 protein|ESCRT-I complex subunit TSG101|TSG101
Gene ID
7251
UniProt
Q99816
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Tumor susceptibility gene 101
Target
TSG101
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Cell Division and Proliferation, Cardiovascular, Metabolism, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
44 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

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