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TRIM37 antibody

CAT: 0710-FNab08982Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab08982Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
E3 ubiquitin-protein ligase required to prevent centriole reduplication (PubMed:15885686, PubMed:23769972) . Probably acts by ubiquitinating positive regulators of centriole reduplication (PubMed:23769972) . Mediates monoubiquitination of 'Lys-119' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression: associates with some Polycomb group (PcG) multiprotein PRC2-like complex and mediates repression of target genes (PubMed:25470042) . Has anti-HIV activity (PubMed:24317724) .
Synonyms
E3 ubiquitin-protein ligase TRIM37|Mulibrey nanism protein|RING-type E3 ubiquitin transferase TRIM37|Tripartite motif-containing protein 37|TRIM37|KIAA0898|MUL|POB1
Gene ID
4591
UniProt
O94972
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Tripartite motif-containing 37
Target
TRIM37
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Epigenetics, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
100 kDa, 130 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF

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