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TF antibody

CAT: 0710-FNab08930Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab08930Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Serotransferrin (TF) is a 77 kDa secreted protein which is also named as transferrin, siderophilin, beta-1 metal-binding globulin and belongs to a family of homologous iron-binding glycoproteins that encompasses lactoferrin (found both intracellular and in secretions, including milk), melanotrasferrin (present on melanoma cells) and ovotransferrin (present in egg white) . TF is a multi-function protein with a primary role in transporting iron in a safe, redox-inactive state from absorption to utilization or storage sites around the body. The association of Tf with the immune system derives from its ability to restrict serum free-iron levels, creating low-iron environments where the infection capacity of pathogenic microorganisms is limited. TF is expressed predominantly in the liver and secreted in plasma, but lower amounts can be synthesized in other tissues such as the brain and the testis
Synonyms
Serotransferrin (Transferrin) |Beta-1 metal-binding globulin|Siderophilin|TF
Gene ID
7018
UniProt
P02787
Host
Mouse
Reactivity
Human
Immunogen
Transferrin
Target
TF
Clonality
Monoclonal
Isotype
IgG1
Applications
ELISA, WB, IHC
Field of Research
Cardiovascular
Purification
Protein A+G purification
Dilution
WB: 1:2000-1:20000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
77 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
6G10
Tested Applications
ELISA, WB, IHC

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