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TMEM106B antibody

CAT: 0710-FNab08745Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab08745Size:100 µg
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Background
Involved in dendrite morphogenesis and maintenance by regulating lysosomal trafficking via its interaction with MAP6. May act by inhibiting retrograde transport of lysosomes along dendrites. Required for dendrite branching.
Synonyms
Transmembrane protein 106B|TMEM106B
Gene ID
54664
UniProt
Q9NUM4
Host
Mouse
Reactivity
Human
Immunogen
Transmembrane protein 106B
Target
TMEM106B
Clonality
Monoclonal
Isotype
IgG1
Applications
ELISA, WB, IHC
Field of Research
Neuroscience, Epigenetics
Purification
Protein A+G purification
Dilution
WB: 1:500-1:2000; IHC: 1:50-1:500
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
40 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
6H1
Tested Applications
ELISA, WB, IHC
Immunogen Sequence
1-50aa

UniProtKB · Q9NUM4

Transmembrane protein 106B

T106B_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9NUM4
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
TMEM106B
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A4D108, Q53FL9, Q8N4L0
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Disease

Amyotrophic lateral sclerosisDisease variantLeukodystrophyNeurodegeneration

Cellular component

Cell membraneEndosomeLysosomeMembrane

PTM

Disulfide bondGlycoproteinLipoproteinMyristatePhosphoprotein

Domain

Signal-anchorTransmembraneTransmembrane helix

Biological process

Transport

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