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TFB2M antibody

CAT: 0710-FNab08622Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab08622Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity.
Synonyms
Dimethyladenosine transferase 2, mitochondrial|Hepatitis C virus NS5A-transactivated protein 5 (HCV NS5A-transactivated protein 5) |Mitochondrial 12S rRNA dimethylase 2|Mitochondrial transcription factor B2 (h-mtTFB, h-mtTFB2, hTFB2M, mtTFB2) |S-adenosylmethionine-6-N', N'-adenosyl (rRNA) dimethyltransferase 2|TFB2M|NS5ATP5
Gene ID
64216
UniProt
Q9H5Q4
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Transcription factor B2, mitochondrial
Target
TFB2M
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
45-50 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

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