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ELOC antibody

CAT: 0710-FNab08548Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab08548Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes the protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been identified.
Synonyms
Elongin-C (EloC) |Elongin 15 kDa subunit|RNA polymerase II transcription factor SIII subunit C|SIII p15|Transcription elongation factor B polypeptide 1|ELOC|TCEB1
Gene ID
6921
UniProt
Q15369
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
Target
ELOC
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
13 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

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