FR054

• Description :

  FR054 is an inhibitor of the HBP enzyme PGM3, with a remarkable anti-breast cancer effect[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Phosphatase

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/fr054.html

• Purity :

  99.46

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  CC(O[C@@H]1[C@]2([H])[C@](OC(C)=N2)([H])O[C@@H]([C@H]1OC(C)=O)COC(C)=O)=O

• Molecular Formula :

  C14H19NO8

• Molecular Weight :

  329.30

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Francesca Ricciardiello, et al. Inhibition of the Hexosamine Biosynthetic Pathway by targeting PGM3 causes breast cancer growth arrest and apoptosis. Cell Death Dis. 2018 Mar 7;9 (3) :377.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C (Powder, sealed storage, away from moisture)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [35954-65-5]