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SUN1 antibody

CAT: 0710-FNab08392Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab08392Size:100 µg
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Background
Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Required for interkinetic nuclear migration (INM) and essential for nucleokinesis and centrosome-nucleus coupling during radial neuronal migration in the cerebral cortex and during glial migration. Anchors chromosome movement in the prophase of meiosis and is involved in selective gene expression of coding and non-coding RNAs needed for gametogenesis. Required for telomere attachment to nuclear envelope and gametogenesis. Helps to define the distribution of nuclear pore complexes (NPCs) (By similarity) . Required for efficient localization of SYNE4 in the nuclear envelope (By similarity) .
Synonyms
SUN domain-containing protein 1|Protein unc-84 homolog A|Sad1/unc-84 protein-like 1|SUN1|KIAA0810|UNC84A
Gene ID
6821
UniProt
O94901
Host
Rabbit
Reactivity
Human
Immunogen
Unc-84 homolog A (C. elegans)
Target
SUN1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Cell Division and Proliferation
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:5000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
90 kDa
Storage Conditions
PBS with 0.1% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

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