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STEAP3 antibody

CAT: 0710-FNab08318Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab08318Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe (3+) to Fe (2+) . Can also reduce of Cu (2+) to Cu (1+), suggesting that it participates in copper homeostasis. Uses NADP (+) as acceptor. May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.
Synonyms
Metalloreductase STEAP3|Dudulin-2|Six-transmembrane epithelial antigen of prostate 3|Tumor suppressor-activated pathway protein 6 (hTSAP6) |pHyde (hpHyde) |STEAP3|TSAP6
Gene ID
55240
UniProt
Q658P3
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
STEAP family member 3
Target
STEAP3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF, IHC, IP
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
55 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF, IHC, IP

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