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SSRP1 antibody

CAT: 0710-FNab08250Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab08250Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known.
Synonyms
FACT complex subunit SSRP1|Chromatin-specific transcription elongation factor 80 kDa subunit|Facilitates chromatin transcription complex 80 kDa subunit (FACT 80 kDa subunit, FACTp80) |Facilitates chromatin transcription complex subunit SSRP1|Recombination signal sequence recognition protein 1|Structure-specific recognition protein 1 (hSSRP1) |T160|SSRP1|FACT80
Gene ID
6749
UniProt
Q08945
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Structure specific recognition protein 1
Target
SSRP1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:10 - 1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
90 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF