SRGAP1 antibody

• Background :

  GTPase-activating protein for RhoA and Cdc42 small GTPases. Together with CDC42 seems to be involved in the pathway mediating the repulsive signaling of Robo and Slit proteins in neuronal migration. SLIT2, probably through interaction with ROBO1, increases the interaction of SRGAP1 with ROBO1 and inactivates CDC42.

• Synonyms :

  SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) |Rho GTPase-activating protein 13|SRGAP1|ARHGAP13|KIAA1304

• Gene ID :

  57522

• UniProt :

  Q7Z6B7

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  SLIT-ROBO Rho GTPase activating protein 1

• Target :

  SRGAP1

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, WB, IHC, IP

• Field of Research :

  Neuroscience, Signal Transduction

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500-1:5000; IP: 1:200-1:2000; IHC: 1:20-1:200

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  130 kDa

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, WB, IHC, IP