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SPRR1B antibody

CAT: 0710-FNab08194Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab08194Size:100 µg
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Background
Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. Can function as both amine donor and acceptor in transglutaminase-mediated cross-linkage.
Synonyms
Cornifin-B|14.9 kDa pancornulin|Small proline-rich protein IB (SPR-IB) |SPRR1B
Gene ID
6699
UniProt
P22528
Host
Rabbit
Reactivity
Human
Immunogen
Small proline-rich protein 1B (cornifin)
Target
SPRR1B
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC
Field of Research
Developmental biology
Purification
Immunogen affinity purified
Dilution
IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC

UniProtKB · P22528

Cornifin-B

SPR1B_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P22528
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SPRR1B
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B2R5H7, P22529, P22530, Q5T524
Protein keywords

Cellular component

Cytoplasm

Technical term

Direct protein sequencingProteomics identificationReference proteome

Biological process

Keratinization

Domain

Repeat