SPI1 antibody

• Background:

  Binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Also binds RNA and may modulate pre-mRNA splicing (By similarity) .

• Synonyms:

  Transcription factor PU.1|31 kDa-transforming protein|SPI1

• Gene ID:

  6688

• UniProt:

  P17947

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Spleen focus forming virus (SFFV) proviral integration oncogene spi1

• Target:

  SPI1

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB

• Field of Research:

  Epigenetics, Signal Transduction, Metabolism

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:2000

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  31-38 kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB