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SPATA13 antibody

CAT: 0710-FNab08158Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab08158Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Regulates cell migration and adhesion assembly and disassembly through a RAC1, PI3K, RHOA and AKT1-dependent mechanism. Increases both RAC1 and CDC42 activity, but decreases the amount of active RHOA. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression.
Synonyms
Spermatogenesis-associated protein 13|APC-stimulated guanine nucleotide exchange factor 2 (Asef2) |SPATA13
Gene ID
221178
UniProt
Q96N96
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Spermatogenesis associated 13
Target
SPATA13
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF
Field of Research
Neuroscience, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
75 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF

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