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SPARC antibody

CAT: 0710-FNab08153Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab08153Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a cysteine-rich acidic matrix-associated protein. The encoded protein is required for the collagen in bone to become calcified but is also involved in extracellular matrix synthesis and promotion of changes to cell shape. The gene product has been associated with tumor suppression but has also been correlated with metastasis based on changes to cell shape which can promote tumor cell invasion. Three transcript variants encoding different isoforms have been found for this gene.
Synonyms
SPARC|Basement-membrane protein 40 (BM-40) |Osteonectin (ON) |Secreted protein acidic and rich in cysteine|SPARC|ON
Gene ID
6678
UniProt
P09486
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Secreted protein, acidic, cysteine-rich (osteonectin)
Target
SPARC
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Stem Cells, Immunology, Cardiovascular, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
35 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF
Immunogen Sequence
1-300aa

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