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SPAG8 antibody

CAT: 0710-FNab08146Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab08146Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Plays a role in spermatogenesis by enhancing the binding of CREM isoform tau to its coactivator FHL5 and increasing the FHL5-regulated transcriptional activation of CREM isoform tau (By similarity) . Involved in the acrosome reaction and in binding of sperm to the zona pellucida (By similarity) . Plays a role in regulation of the cell cycle by controlling progression through the G2/M phase, possibly by delaying the activation of CDK1 which is required for entry into mitosis (PubMed:19548270) . May play a role in fertility and microtubule formation through interaction with RANBP9 (PubMed:10500252) .
Synonyms
Sperm-associated antigen 8|HSD-1|Sperm membrane protein 1 (SMP-1) |Sperm membrane protein BS-84|SPAG8
Gene ID
26206
UniProt
Q99932
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Sperm associated antigen 8
Target
SPAG8
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IP
Field of Research
Stem Cells
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
56-65 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IP

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