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SORL1 antibody

CAT: 0710-FNab08116Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab08116Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Synonyms
Sortilin-related receptor|Low-density lipoprotein receptor relative with 11 ligand-binding repeats (LDLR relative with 11 ligand-binding repeats, LR11) |SorLA-1|Sorting protein-related receptor containing LDLR class A repeats (SorLA) |SORL1|C11orf32
UniProt
Q92673
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Sortilin-related receptor, L (DLR class) A repeats-containing
Target
SORL1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IP, IHC
Field of Research
Neuroscience, Metabolism
Purification
Immunogen affinity purified
Dilution
IP: 1:200-1:1000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IP, IHC
Immunogen Sequence
2000-2214aa

UniProtKB · Q92673

Sortilin-related receptor

SORL_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q92673
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SORL1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
B2RNX7, Q92856
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Disease

Alzheimer diseaseAmyloidosisDisease variantNeurodegeneration

Cellular component

Cell membraneCytoplasmic vesicleEndoplasmic reticulumEndosomeGolgi apparatusMembraneSecreted

PTM

Cleavage on pair of basic residuesDisulfide bondGlycoproteinPhosphoprotein

Domain

EGF-like domainRepeatSignalTransmembraneTransmembrane helix

Biological process

EndocytosisProtein transportTransport

Molecular function

Receptor

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