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SORBS2 antibody

CAT: 0710-FNab08112Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab08112Size:100 µg
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Background
Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 or with AKT1 and PAK1, thus mediating AKT1-mediated activation of PAK1. May play a role in the regulation of pancreatic cell adhesion, possibly by acting on WASF1 phosphorylation, enhancing phosphorylation by ABL1, as well as dephosphorylation by PTPN12 (PubMed:18559503) . Isoform 6 increases water and sodium absorption in the intestine and gall-bladder.
Synonyms
Sorbin and SH3 domain-containing protein 2|Arg-binding protein 2 (ArgBP2) |Arg/Abl-interacting protein 2|Sorbin|SORBS2|ARGBP2|KIAA0777
Gene ID
8470
UniProt
O94875
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Sorbin and SH3 domain containing 2
Target
SORBS2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IP
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
IP: 1:200-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IP

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