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SMG5 antibody

CAT: 0710-FNab08025Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab08025Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Plays a role in nonsense-mediated mRNA decay. Does not have RNase activity by itself. Promotes dephosphorylation of UPF1. Together with SMG7 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation. Necessary for TERT activity.
Synonyms
Nonsense-mediated mRNA decay factor SMG5|EST1-like protein B|LPTS-RP1|LPTS-interacting protein|SMG-5 homolog (hSMG-5) |SMG5|EST1B|KIAA1089
Gene ID
23381
UniProt
Q9UPR3
Host
Rabbit
Reactivity
Human
Immunogen
Smg-5 homolog, nonsense mediated mRNA decay factor
Target
SMG5
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Epigenetics
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
114 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

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