SMG5 antibody
CAT:
710-FNab08025
Size:
100 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
SMG5 antibody
- Background: Plays a role in nonsense-mediated mRNA decay. Does not have RNase activity by itself. Promotes dephosphorylation of UPF1. Together with SMG7 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A(PP2A), thereby triggering UPF1 dephosphorylation. Necessary for TERT activity.
- Synonyms: Nonsense-mediated mRNA decay factor SMG5|EST1-like protein B|LPTS-RP1|LPTS-interacting protein|SMG-5 homolog (hSMG-5)|SMG5|EST1B|KIAA1089
- CAS Number: 9007-83-4
- Gene ID: 23381
- UniProt: Q9UPR3
- Host: Rabbit
- Reactivity: Human
- Immunogen: Smg-5 homolog, nonsense mediated mRNA decay factor
- Target: SMG5
- Clonality: Polyclonal
- Isotype: IgG
- Applications: ELISA, WB
- Field of Research: Epigenetics
- Purification: Immunogen affinity purified
- Dilution: WB: 1:500-1:2000
- Purity: ≥95% as determined by SDS-PAGE
- Form: Liquid
- Molecular Weight: 114 kDa
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)