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SLC37A4 antibody

CAT: 0710-FNab07958Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab07958Size:100 µg
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Background
Inorganic phosphate and glucose-6-phosphate antiporter of the endoplasmic reticulum. Transports cytoplasmic glucose-6-phosphate into the lumen of the endoplasmic reticulum and translocates inorganic phosphate into the opposite direction. Forms with glucose-6-phosphatase the complex responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it plays a central role in homeostatic regulation of blood glucose levels.
Synonyms
Glucose-6-phosphate exchanger SLC37A4|Glucose-5-phosphate transporter|Glucose-6-phosphate translocase|Solute carrier family 37 member 4|Transformation-related gene 19 protein (TRG-19) |SLC37A4|G6PT|G6PT1
Gene ID
2542
UniProt
O43826
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Solute carrier family 37 (glucose-6-phosphate transporter), member 4
Target
SLC37A4
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Cardiovascular, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
46 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

UniProtKB · O43826

Glucose-6-phosphate exchanger SLC37A4

G6PT1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O43826
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SLC37A4
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
O96016, Q5J7V4, Q9UI19, Q9UNS4
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

AntiportSugar transportTransport

Disease

Congenital disorder of glycosylationDisease variantGlycogen storage disease

Cellular component

Endoplasmic reticulumMembrane

Domain

TransmembraneTransmembrane helix