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SIAH1 antibody

CAT: 0710-FNab07857Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab07857Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.
Synonyms
E3 ubiquitin-protein ligase SIAH1|RING-type E3 ubiquitin transferase SIAH1|Seven in absentia homolog 1 (Siah-1) |Siah-1a|SIAH1|HUMSIAH
Gene ID
6477
UniProt
Q8IUQ4
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Seven in absentia homolog 1 (Drosophila)
Target
SIAH1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Neuroscience, Epigenetics, Metabolism, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
31 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF

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