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SEC13 antibody

CAT: 0710-FNab07677Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab07677Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Functions as a component of the nuclear pore complex (NPC) and the COPII coat. At the endoplasmic reticulum, SEC13 is involved in the biogenesis of COPII-coated vesicles. As a component of the GATOR subcomplex GATOR2, functions as an activator of the amino acid-sensing branch of the TORC1 pathway. Inhibits the GATOR1 subcomplex, an inhibitor of the amino acid-sensing branch of the TORC1 pathway (PubMed:23723238) . Functions downstream and is regulated by amino acid sensors like SESN2 (Probable) .
Synonyms
Protein SEC13 homolog|GATOR2 complex protein SEC13|SEC13-like protein 1|SEC13-related protein|SEC13|D3S1231E|SEC13A|SEC13L1|SEC13R
Gene ID
6396
UniProt
P55735
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
SEC13 homolog
Target
SEC13
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF, IP
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
36 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF, IP

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