SEC13 antibody

• Background:

  Functions as a component of the nuclear pore complex (NPC) and the COPII coat. At the endoplasmic reticulum, SEC13 is involved in the biogenesis of COPII-coated vesicles. As a component of the GATOR subcomplex GATOR2, functions as an activator of the amino acid-sensing branch of the TORC1 pathway. Inhibits the GATOR1 subcomplex, an inhibitor of the amino acid-sensing branch of the TORC1 pathway (PubMed:23723238) . Functions downstream and is regulated by amino acid sensors like SESN2 (Probable) .

• Synonyms:

  Protein SEC13 homolog|GATOR2 complex protein SEC13|SEC13-like protein 1|SEC13-related protein|SEC13|D3S1231E|SEC13A|SEC13L1|SEC13R

• Gene ID:

  6396

• UniProt:

  P55735

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  SEC13 homolog

• Target:

  SEC13

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC, IF, IP

• Field of Research:

  Metabolism

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  36 kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC, IF, IP