SDHA antibody

• Background :

  This gene encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. Mutations in this gene have been associated with a form of mitochondrial respiratory chain deficiency known as Leigh Syndrome. A pseudogene has been identified on chromosome 3q29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• Synonyms :

  Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial|Flavoprotein subunit of complex II (Fp) |SDHA|SDH2|SDHF

• Gene ID :

  6389

• UniProt :

  P31040

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Succinate dehydrogenase complex, subunit A, flavoprotein (Fp)

• Target :

  SDHA

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, WB, IHC, IF

• Field of Research :

  Metabolism, Developmental biology

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:10 - 1:100

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  70 kDa

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, WB, IHC, IF