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SCNN1G antibody

CAT: 0710-FNab07649Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab07649Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the gamma subunit, and mutations in this gene have been associated with Liddle syndrome.
Synonyms
Amiloride-sensitive sodium channel subunit gamma|Epithelial Na (+) channel subunit gamma (ENaCG, Gamma-ENaC) |Gamma-NaCH|Nonvoltage-gated sodium channel 1 subunit gamma|SCNEG|SCNN1G
Gene ID
6340
UniProt
P51170
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Sodium channel, nonvoltage-gated 1, gamma
Target
SCNN1G
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Neuroscience
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:1000; IHC: 1:50 - 1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
80 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

UniProtKB · P51170

Epithelial sodium channel subunit gamma

SCNNG_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P51170
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SCNN1G
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
ENaC subunit gamma, ENaCG, Epithelial Na(+) channel subunit gamma, Gamma-ENaC
EC number
—
Processing
—
Secondary accessions
P78437, Q6PCC2, Q93023, Q93024, Q93025, Q93026, Q93027, Q96TD2
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Cellular component

Cell membraneMembrane

Disease

Disease variant

PTM

Disulfide bondGlycoproteinPhosphoproteinUbl conjugation

Molecular function

Ion channelSodium channel

Biological process

Ion transportSodium transportTransport

Ligand

Sodium

Domain

TransmembraneTransmembrane helix

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