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SBDS antibody

CAT: 0710-FNab07617Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab07617Size:100 µg
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Background
This gene encodes a highly conserved protein that plays an essential role in ribosome biogenesis. The encoded protein interacts with elongation factor-like GTPase 1 to disassociate eukaryotic initiation factor 6 from the late cytoplasmic pre-60S ribosomal subunit allowing assembly of the 80S subunit. Mutations within this gene are associated with the autosomal recessive disorder Shwachman-Bodian-Diamond syndrome. This gene has a closely linked pseudogene that is distally located.
Synonyms
Ribosome maturation protein SBDS|Shwachman-Bodian-Diamond syndrome protein|SBDS
Gene ID
51119
UniProt
Q9Y3A5
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Shwachman-Bodian-Diamond syndrome
Target
SBDS
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
34 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF

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